NICHD Clinical Trials
Researchers from the Division of Intramural Research are participating in all of the following protocols.
Found 113 results
Protocol #
|
Protocol Title | Principal Investigator |
Branch |
|---|---|---|---|
| 00-CH-0035 | The Development of Categorization | Marc H. Bornstein, Ph.D. | CE |
| 00-CH-0093 | Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and Paraganglioma | Karel Pacak, M.D. | RE |
| 00-CH-0127 | Evaluation of Patients with Endocrine-Related Conditions | Smita K. Baid, M.D. | RE |
| 00-CH-0134 | Effects of Metformin on Energy Intake, Energy Expenditure, and Body Weight in Overweight Children with Insulin Resistance | Jack A. Yanovski, M.D. | DE |
| 00-CH-0136 | A Trial of Pamidronate in Children with Osteogenesis Imperfecta | Joan C. Marini, M.D. | BE |
| 00-CH-0160 | Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue | Constantine A. Stratakis, M.D. | DE |
| 00-CH-0180 | Endocrine Studies in Health and Disease | Carolyn A. Bondy, M.D. | DE |
| 00-CH-0189 | FSH-Stimulated Inhibin B as a Marker for Early Ovarian Insufficiency | Lawrence M. Nelson, M.D. | RE |
| 00-CH-0219 | Turner Syndrome: Genotype and Phenotype | Carolyn A. Bondy, M.D. | DE |
| 01-CH-0086 | A Combination Therapy with Cystagon and N-Acetylcysteine for INCL Patients | Anil B. Mukherjee, M.D. | DE |
| 01-CH-0096 | Catecholamine Reserve and Exercise Tolerance in Subjects with Congenital Adrenal Hyperplasia and in Healthy Controls | Deborah P. Merke, M.D. | OD |
| 02-CH-0023 | Studies of Pediatric Patients with Metabolic or Other Genetic Disorders | Margarita Raygada, Ph.D. | OD |
| 02-CH-0100 | Supplemental Calcium in Overweight Out-Patients | Jack A. Yanovski, M.D. | DE |
| 02-CH-0195 | Human MATER and Idiopathic Infertility | Lawrence M. Nelson, M.D. | RE |
| 02-CH-0278 | Dyadic Interactions in Depressed and Non-Depressed Mothers with Their Infants | Marc H. Bornstein, Ph.D. | CE |
| 02-CH-0287 | Treatment of Leiomyomata with the Selective Progesterone Receptor Modulator CDB-2914 | Lynnette K. Nieman, M.D. | RE |
| 02-CH-0309 | The Diagnostic Performance of Screening Tests for the Diagnosis of Cushing's Syndrome | Lynnette K. Nieman, M.D. | RE |
| 02-CH-0311 | Investigations into Inborn Errors of Cholesterol Synthesis and Related Disorders | Forbes D. Porter, M.D. | DE |
| 02-CH-N261 | A Prospective, Observational Study of HIV-Infected Pregnant Women and HIV-Exposed, Uninfected Children at Clinical Sites in Latin American Countries | Jennifer S. Read, M.D. | PA |
| 02-CH-N270 | NISDI Pediatric Latin American Countries Epidemiologic Study (PLACES): A Prospective Observational Study of HIV-Infected Children at Clinical Sites in Latin American Countries | Rohan Hazra, M.D. | AB |
| 03-CH-0060 | Virtual Functional Anatomy (VFA) | Frances Gavelli, Ph.D. | RE |
| 03-CH-0069 | Early Learning and Development Project | Clay W. Mash, Ph.D. | CE |
| 03-CH-0225 | Investigation of Simvastatin Therapy in Smith-Lemli-Opitz Syndrome | Forbes D. Porter, M.D. | DE |
| 03-CH-N076 | Methylenetetrahydrofolate Reductase C677T Mutation, Other Variant Genotypes, and Male Infertility | Richard J. Levine, M.D. | OD |
| 03-CH-N141 | Environmental and Behavioral Risk Factors for Childhood Drowning | Ruth Brenner, M.D. | EB |
| 03-CH-N261 | Steppin' Up: Positive Youth Development Program | Bruce Simons-Morton, M.D. | PR |
| 04-CH-0050 | Eating Behavior in Children | Jack A. Yanovski, M.D. | DE |
| 04-CH-0056 | The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with Endometriosis | Pamela Stratton, M.D. | RE |
| 04-CH-0077 | Screening and Diagnosis of Patients With Connective Tissue Disorders | Joan C. Marini, M.D. | BE |
| 04-CH-0250 | Event Related Potentials in Infants and Adults | Marc H. Bornstein, Ph.D. | CE |
| 04-CH-0283 | Anthrax Vaccine Clinical Trials | Rachel Schneerson, M.D. | DM |
| 05-CH-0013 | Adrenal Function in Critical Illness | Lynnette K. Nieman, M.D. | RE |
| 05-CH-0037 | The Effects of Hydrocortisone, Melatonin, and Placebo on Symptoms of Jet Lag | Lynnette K. Nieman, M.D. | RE |
| 05-CH-0168 | Short-Term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome | Forbes D. Porter, M.D. | DE |
| 05-CH-0204 | Hypertonia in Patients with Cerebral Palsy | Maria Lebiedowska, Ph.D. | RE |
| 05-CH-N030 | Family Management of Childhood Diabetes Study | Tonja R. Nansel, Ph.D. | PR |
| 05-CH-N083 | Building Healthy Teen Relationships and Reproductive Practices to Increase Interpregnancy Intervals | Michele Kiely, Ph.D. | ER |
| 05-CH-N211 | Prevention of Environmental Tobacco Smoke (ETS) Exposure to Children, Ages 0-12 Months | Michele Kiely, Ph.D. | ER |
| 05-CH-N227 | Nicotine Replacement Therapy Methods for Pregnant Minority Women | Michele Kiely, Ph.D. | ER |
| 06-CH-0010 | Remodeling of Chromatin-Based Epigenetic Structures in Development and Aging | Bruce H. Howard, M.D. | GR |
| 06-CH-0011 | Natural History Study of Patients with Excess Androgen | Deborah P. Merke, M.D. | OD |
| 06-CH-0038 | Body Heat Content and Dissipation in Obese and Normal Weight Adults | Jack A. Yanovski, M.D. | DE |
| 06-CH-0039 | Pilot Program for Targeted Prevention of Adolescent Weight Gain | Jack A. Yanovski, M.D. | DE |
| 06-CH-0090 | Evaluation of Whether the Selective Progesterone Receptor Modulator CDB-2914 Can Shrink Leiomyomata | Lynnette K. Nieman, M.D. | RE |
| 06-CH-0119 | Insulin Resistance and Breast Cancer: Implications for Preventive Counseling in Familial and Sporadic Cases | Margarita Raygada, Ph.D. | OD |
| 06-CH-0186 | Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C | Forbes D. Porter, M.D. | DE |
| 06-CH-0201 | Effect of Transdermal Estradiol Replacement Therapy on Ovulation Rate in Women with Premature Ovarian Failure: A Randomized, Placebo-Controlled Trial | Lawrence M. Nelson, M.D. | RE |
| 06-CH-0223 | Biobehavioral Study of Recently Adopted Children | Margaret F. Keil, C.R.N.P. | DE |
| 06-CH-N078 | Adolescent Pregnancy Prevention: Building Futures for Youth | Michele Kiely, Ph.D. | ER |
| 06-CH-N094 | An Exercise Intervention in Insulin-Resistant Minority Adolescents | Michele Kiely, Ph.D. | ER |
| 06-CH-N191 | National Electronic Injury Surveillance System (NEISS) Special Study on Injuries among Youth with Developmental Disabilities | Germaine M. Louis, M.D. | ER |
| 07-CH-0008 | Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion | Lynnette K. Nieman, M.D. | RE |
| 07-CH-0126 | Pilot Study of the Metabolic Effects of Betahistine Hydrochloride (Obecure) in Overweight Women | Jack A. Yanovski, M.D. | DE |
| 07-CH-0169 | Noninvasive Optical Imaging of the Effects of External Spectral Filters on Macular Autofluorescence in Pseudophakic Eyes | Robert F. Bonner, Ph.D. | IM |
| 07-CH-0192 | Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors | Maya B. Lodish, M.D. | DE |
| 07-CH-0193 | Use of GnRH Antagonist to Preserve Ovarian Function in Women Undergoing Chemotherapy | Alicia Y. Armstrong, M.D. | RE |
| 07-CH-N199 | Tobacco Smoke and Lead Exposure during Pregnancy: Intervention to Reduce Effects on Birth-Weight and Gestational Age | Michele Kiely, Ph.D. | ER |
| 08-CH-0001 | Calibration of Non-Invasive Non-Ionizing Imaging Techniques to Study Vasculature of Healthy Volunteers | Amir Gandjbakhche, Ph.D. | IM |
| 08-CH-0022 | Treatment of Menorrhagia in Women with Thrombocytopenia: Comparison of Platelet Transfusion Alone to Platelet Transfusion with Continuous Oral Contraceptive Pills | Pamela Stratton, M.D. | RE |
| 08-CH-0085 | Eating Behavior in Adolescents | Jack A. Yanovski, M.D. | DE |
| 08-CH-0139 | Preventing Excessive Weight Gain in Adolescent Girls at High-Risk for Adult Obesity | Jack A. Yanovski, M.D. | DE |
| 08-CH-0170 | Establishment of a Fibroid Tissue Bank | James H. Segars Jr., M.D. | RE |
| 08-CH-0203 | A Pilot Study to Assess the Feasibility of PTH 1-34 Therapy via Pump in the Management of Chronic Hypoparathyroidism | Karen K. Winer, M.D. | RE |
| 08-CH-0213 | WAGR Syndrome and Other 11p Contiguous Gene Deletions: Clinical Characterization and Correlation with Genotype | Joan C. Han, M.D. | DE |
| 08-CH-N011 | Expression Profiling of Bacterial Lipopolysaccharide Activated Neutrophil in Preterm, Term Infants and Adults | Wai-Yee Chan, Ph.D. | CG |
| 08-CH-N050 | Carrier Frequency of a Recurring Mutation Causing Recessive Type VIII Osteogenesis Imperfecta in African-Americans from Maryland and the District of Columbia, and Contemporary West Africans from Ghana and Nigeria | Joan C. Marini, M.D. | BE |
| 08-CH-N069 | Respiratory Distress of the Newborn and Its Relationship to Group B Streptococcal Colonization | Feng-Ying C. Lin, M.D. | OD |
| 08-CH-N183 | Teenage Passenger Influences on the Simulated Driving Performance of Teenage Drivers | Bruce Simons-Morton, M.D. | PR |
| 09-CH-0059 | Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency | Stephen G. Kaler, M.D. | OD |
| 09-CH-0063 | Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids | Pamela Stratton, M.D. | RE |
| 09-CH-0085 | Global Study of Women's Health | Pamela Stratton, M.D. | RE |
| 09-CH-0180 | Non-Invasive Non-Ionizing Polarized Imaging System to Assess Structure of Cervix | Amir Gandjbakhche, Ph.D. | IM |
| 09-CH-0185 | Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl Cysteine | Forbes D. Porter, M.D. | DE |
| 09-CH-0203 | Cholesterol in Autism Spectrum Disorder (ASD): Characterization and Treatment | Forbes D. Porter, M.D. | DE |
| 09-CH-0213 | Malaria Transmission-Blocking Pfs25-Pfs25 Conjugate Vaccine | Rachel Schneerson, M.D. | DM |
| 09-CH-N014 | The Effect of Vaginal Progesterone Administration in the Prevention of Preterm Birth in Women with a Short Cervix | Roberto Romero, M.D. | PR |
| 09-CH-N023 | Health Behaviors in School-Age Children: 2009/2010 | Ronald Iannotti, Ph.D. | PR |
| 09-CH-N083 | The National Children's Study - Pilot Protocol | Steven Hirschfeld, M.D. | PB |
| 09-CH-N152 | The National Standard for Normal Fetal Growth | Jun Zhang, M.D. | EB |
| 09-CH-N165 | Preventing Motor Vehicle Crashes Among Young Drivers: Evaluation of the Checkpoints Program Presented by the American Automobile Association | Bruce Simons-Morton, M.D. | PR |
| 09-CH-N231 | Health Behavior in School-Age Children: NEXT Longitudinal Study 2009-2013 | Ronald Iannotti, Ph.D. | PR |
| 09-CH-N234 | Cultivating Healthy Environments in Families with Type 1 Diabetes (CHEF) | Tonja R. Nansel, Ph.D. | PR |
| 84-CH-0169 | Endocrine Studies of Healthy Children | Jack A. Yanovski, M.D. | DE |
| 88-CH-0032 | Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood Status | Marc H. Bornstein, Ph.D. | CE |
| 90-CH-0149 | Early Copper Histidine Therapy in Menkes Disease | Stephen G. Kaler, M.D. | OD |
| 91-CH-0127 | Ovarian Follicle Function in Patients with Premature Ovarian Failure | Lawrence M. Nelson, M.D. | RE |
| 92-CH-0011 | Treatment of Hypoparathyroidism with Synthetic Human Parathyroid Hormone 1-34 | Karen K. Winer, M.D. | RE |
| 92-CH-0034 | Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IV | Joan C. Marini, M.D. | BE |
| 92-CH-0223 | Autoimmune Premature Ovarian Failure: A Controlled Trial of Alternate-Day Prednisone Therapy | Lawrence M. Nelson, M.D. | RE |
| 95-CH-0059 | Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related Conditions | Constantine A. Stratakis, M.D. | DE |
| 95-CH-0104 | Internal Jugular Vein Sampling for ACTH Levels for the Differential Diagnosis of Cushing Syndrome | Lynnette K. Nieman, M.D. | RE |
| 95-CH-0110 | Endometrial Mediators of Gonadal Steroid Action | Lynnette K. Nieman, M.D. | RE |
| 96-CH-0033 | An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal Hyperplasia | Deborah P. Merke, M.D. | OD |
| 96-CH-0101 | Population Differences in the Insulin Sensitivity, Resting Energy Expenditure, and Body Composition of Overweight Children and Children of Overweight Parents | Jack A. Yanovski, M.D. | DE |
| 97-CH-0064 | Evaluation and Intervention for Ambulation, Basilar Invagination, and Secondary Effects of Osteogenesis Imperfecta | Joan C. Marini, M.D. | BE |
| 97-CH-0076 | A Clinical and Genetic Investigation of Pituitary Tumors and Related Hypothalmic Disorders | Constantine A. Stratakis, M.D. | DE |
| 98-CH-0081 | Clinical and Basic Investigations into Smith-Lemli-Opitz Syndrome | Forbes D. Porter, M.D. | DE |
| 98-CH-0111 | Safety and Efficacy of Orlistat (Xenical, Hoffmann LaRoche) in African American and Caucasian Children and Adolescents with Obesity-Related Comorbid Conditions | Jack A. Yanovski, M.D. | DE |
| 98-CH-0155 | Categorization Based on Motion-Carried Information in Infancy | Marc H. Bornstein, Ph.D. | CE |
| 99-CH-0055 | New Imaging Modalities in the Evaluation of Patients with Ectopic Cushing Syndrome | Lynnette K. Nieman, M.D. | RE |
| 99-CH-0103 | Evaluation of Women with Endocrine and Reproductive-Related Conditions | Alicia Y. Armstrong, M.D. | RE |
| OH95-CH-N040 | Use of a Perinatal Database and Biologic Tissue Bank at the Perinatology Research Branch (PRB) | Roberto Romero, M.D. | PR |
| OH97-CH-N065 | Fetal Anatomy by Three-Dimensional Ultrasound | Roberto Romero, M.D. | PR |
| OH97-CH-N066 | Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients with Preterm Labor and Premature Rupture of Membranes | Roberto Romero, M.D. | PR |
| OH97-CH-N067 | Biological Markers of Disease in the Prediction of Preterm Delivery, Preeclampsia and Intra-Uterine Growth Retardation: A Longitudinal Study | Roberto Romero, M.D. | PR |
| OH97-CH-N068 | Fetal Growth Evaluation by Three-Dimensional Ultrasound | Roberto Romero, M.D. | PR |
| OH98-CH-N001 | Establishment of a Clinical Perinatal Database and Bank of Biological Materials | Roberto Romero, M.D. | PR |
| OH98-CH-N016 | Cervical Volume by Three-Dimensional Ultrasound as a Predictor of Preterm Delivery | Roberto Romero, M.D. | PR |
| OH98-CH-N018 | Early Pregnancy Evaluation by Three-Dimensional Ultrasound | Roberto Romero, M.D. | PR |
| OH99-CH-N023 | Longitudinal Study of Vaginal Flora | Mark Klebanoff, M.D. | EB |
| OH99-CH-N050 | Evaluation of the Safety, Immunogenicity and Compatibility with DTP of an Investigational Vi-rEPA(2) Conjugate Vaccine for Typhoid Fever When Administered to Infants in Vietnam Concurrently with DTP | Shousun C. Szu, Ph.D. | DM |
| OH99-CH-N056 | Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition | Roberto Romero, M.D. | PR |
| Pilot Study of L-DOPS for Dysautonomia in Menkes Disease and Occipital Horn Syndrome | Stephen G. Kaler, M.D. | OD |
