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Eunice Kennedy Shriver National Institute of Child Health and Human Development
Division of Intramural Research

Latest DIR Publication

2013 DIR Annual Report Image

For more, visit the Publications pages.

NICHD Clinical Trials

Researchers from the Division of Intramural Research are participating in all of the following protocols.
Found 113 results           
Protocol #   down arrow Protocol Title   Principal
Investigator
 
Branch  
00-CH-0035 The Development of Categorization Marc H. Bornstein, Ph.D. CE
00-CH-0093 Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and Paraganglioma Karel Pacak, M.D. RE
00-CH-0127 Evaluation of Patients with Endocrine-Related Conditions Smita K. Baid, M.D. RE
00-CH-0134 Effects of Metformin on Energy Intake, Energy Expenditure, and Body Weight in Overweight Children with Insulin Resistance Jack A. Yanovski, M.D. DE
00-CH-0136 A Trial of Pamidronate in Children with Osteogenesis Imperfecta Joan C. Marini, M.D. BE
00-CH-0160 Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue Constantine A. Stratakis, M.D. DE
00-CH-0180 Endocrine Studies in Health and Disease Carolyn A. Bondy, M.D. DE
00-CH-0189 FSH-Stimulated Inhibin B as a Marker for Early Ovarian Insufficiency Lawrence M. Nelson, M.D. RE
00-CH-0219 Turner Syndrome: Genotype and Phenotype Carolyn A. Bondy, M.D. DE
01-CH-0086 A Combination Therapy with Cystagon and N-Acetylcysteine for INCL Patients Anil B. Mukherjee, M.D. DE
01-CH-0096 Catecholamine Reserve and Exercise Tolerance in Subjects with Congenital Adrenal Hyperplasia and in Healthy Controls Deborah P. Merke, M.D. OD
02-CH-0023 Studies of Pediatric Patients with Metabolic or Other Genetic Disorders Margarita Raygada, Ph.D. OD
02-CH-0100 Supplemental Calcium in Overweight Out-Patients Jack A. Yanovski, M.D. DE
02-CH-0195 Human MATER and Idiopathic Infertility Lawrence M. Nelson, M.D. RE
02-CH-0278 Dyadic Interactions in Depressed and Non-Depressed Mothers with Their Infants Marc H. Bornstein, Ph.D. CE
02-CH-0287 Treatment of Leiomyomata with the Selective Progesterone Receptor Modulator CDB-2914 Lynnette K. Nieman, M.D. RE
02-CH-0309 The Diagnostic Performance of Screening Tests for the Diagnosis of Cushing's Syndrome Lynnette K. Nieman, M.D. RE
02-CH-0311 Investigations into Inborn Errors of Cholesterol Synthesis and Related Disorders Forbes D. Porter, M.D. DE
02-CH-N261 A Prospective, Observational Study of HIV-Infected Pregnant Women and HIV-Exposed, Uninfected Children at Clinical Sites in Latin American Countries Jennifer S. Read, M.D. PA
02-CH-N270 NISDI Pediatric Latin American Countries Epidemiologic Study (PLACES): A Prospective Observational Study of HIV-Infected Children at Clinical Sites in Latin American Countries Rohan Hazra, M.D. AB
03-CH-0060 Virtual Functional Anatomy (VFA) Frances Gavelli, Ph.D. RE
03-CH-0069 Early Learning and Development Project Clay W. Mash, Ph.D. CE
03-CH-0225 Investigation of Simvastatin Therapy in Smith-Lemli-Opitz Syndrome Forbes D. Porter, M.D. DE
03-CH-N076 Methylenetetrahydrofolate Reductase C677T Mutation, Other Variant Genotypes, and Male Infertility Richard J. Levine, M.D. OD
03-CH-N141 Environmental and Behavioral Risk Factors for Childhood Drowning Ruth Brenner, M.D. EB
03-CH-N261 Steppin' Up: Positive Youth Development Program Bruce Simons-Morton, M.D. PR
04-CH-0050 Eating Behavior in Children Jack A. Yanovski, M.D. DE
04-CH-0056 The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with Endometriosis Pamela Stratton, M.D. RE
04-CH-0077 Screening and Diagnosis of Patients With Connective Tissue Disorders Joan C. Marini, M.D. BE
04-CH-0250 Event Related Potentials in Infants and Adults Marc H. Bornstein, Ph.D. CE
04-CH-0283 Anthrax Vaccine Clinical Trials Rachel Schneerson, M.D. DM
05-CH-0013 Adrenal Function in Critical Illness Lynnette K. Nieman, M.D. RE
05-CH-0037 The Effects of Hydrocortisone, Melatonin, and Placebo on Symptoms of Jet Lag Lynnette K. Nieman, M.D. RE
05-CH-0168 Short-Term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome Forbes D. Porter, M.D. DE
05-CH-0204 Hypertonia in Patients with Cerebral Palsy Maria Lebiedowska, Ph.D. RE
05-CH-N030 Family Management of Childhood Diabetes Study Tonja R. Nansel, Ph.D. PR
05-CH-N083 Building Healthy Teen Relationships and Reproductive Practices to Increase Interpregnancy Intervals Michele Kiely, Ph.D. ER
05-CH-N211 Prevention of Environmental Tobacco Smoke (ETS) Exposure to Children, Ages 0-12 Months Michele Kiely, Ph.D. ER
05-CH-N227 Nicotine Replacement Therapy Methods for Pregnant Minority Women Michele Kiely, Ph.D. ER
06-CH-0010 Remodeling of Chromatin-Based Epigenetic Structures in Development and Aging Bruce H. Howard, M.D. GR
06-CH-0011 Natural History Study of Patients with Excess Androgen Deborah P. Merke, M.D. OD
06-CH-0038 Body Heat Content and Dissipation in Obese and Normal Weight Adults Jack A. Yanovski, M.D. DE
06-CH-0039 Pilot Program for Targeted Prevention of Adolescent Weight Gain Jack A. Yanovski, M.D. DE
06-CH-0090 Evaluation of Whether the Selective Progesterone Receptor Modulator CDB-2914 Can Shrink Leiomyomata Lynnette K. Nieman, M.D. RE
06-CH-0119 Insulin Resistance and Breast Cancer: Implications for Preventive Counseling in Familial and Sporadic Cases Margarita Raygada, Ph.D. OD
06-CH-0186 Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C Forbes D. Porter, M.D. DE
06-CH-0201 Effect of Transdermal Estradiol Replacement Therapy on Ovulation Rate in Women with Premature Ovarian Failure: A Randomized, Placebo-Controlled Trial Lawrence M. Nelson, M.D. RE
06-CH-0223 Biobehavioral Study of Recently Adopted Children Margaret F. Keil, C.R.N.P. DE
06-CH-N078 Adolescent Pregnancy Prevention: Building Futures for Youth Michele Kiely, Ph.D. ER
06-CH-N094 An Exercise Intervention in Insulin-Resistant Minority Adolescents Michele Kiely, Ph.D. ER
06-CH-N191 National Electronic Injury Surveillance System (NEISS) Special Study on Injuries among Youth with Developmental Disabilities Germaine M. Louis, M.D. ER
07-CH-0008 Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion Lynnette K. Nieman, M.D. RE
07-CH-0126 Pilot Study of the Metabolic Effects of Betahistine Hydrochloride (Obecure) in Overweight Women Jack A. Yanovski, M.D. DE
07-CH-0169 Noninvasive Optical Imaging of the Effects of External Spectral Filters on Macular Autofluorescence in Pseudophakic Eyes Robert F. Bonner, Ph.D. IM
07-CH-0192 Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors Maya B. Lodish, M.D. DE
07-CH-0193 Use of GnRH Antagonist to Preserve Ovarian Function in Women Undergoing Chemotherapy Alicia Y. Armstrong, M.D. RE
07-CH-N199 Tobacco Smoke and Lead Exposure during Pregnancy: Intervention to Reduce Effects on Birth-Weight and Gestational Age Michele Kiely, Ph.D. ER
08-CH-0001 Calibration of Non-Invasive Non-Ionizing Imaging Techniques to Study Vasculature of Healthy Volunteers Amir Gandjbakhche, Ph.D. IM
08-CH-0022 Treatment of Menorrhagia in Women with Thrombocytopenia: Comparison of Platelet Transfusion Alone to Platelet Transfusion with Continuous Oral Contraceptive Pills Pamela Stratton, M.D. RE
08-CH-0085 Eating Behavior in Adolescents Jack A. Yanovski, M.D. DE
08-CH-0139 Preventing Excessive Weight Gain in Adolescent Girls at High-Risk for Adult Obesity Jack A. Yanovski, M.D. DE
08-CH-0170 Establishment of a Fibroid Tissue Bank James H. Segars Jr., M.D. RE
08-CH-0203 A Pilot Study to Assess the Feasibility of PTH 1-34 Therapy via Pump in the Management of Chronic Hypoparathyroidism Karen K. Winer, M.D. RE
08-CH-0213 WAGR Syndrome and Other 11p Contiguous Gene Deletions: Clinical Characterization and Correlation with Genotype Joan C. Han, M.D. DE
08-CH-N011 Expression Profiling of Bacterial Lipopolysaccharide Activated Neutrophil in Preterm, Term Infants and Adults Wai-Yee Chan, Ph.D. CG
08-CH-N050 Carrier Frequency of a Recurring Mutation Causing Recessive Type VIII Osteogenesis Imperfecta in African-Americans from Maryland and the District of Columbia, and Contemporary West Africans from Ghana and Nigeria Joan C. Marini, M.D. BE
08-CH-N069 Respiratory Distress of the Newborn and Its Relationship to Group B Streptococcal Colonization Feng-Ying C. Lin, M.D. OD
08-CH-N183 Teenage Passenger Influences on the Simulated Driving Performance of Teenage Drivers Bruce Simons-Morton, M.D. PR
09-CH-0059 Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency Stephen G. Kaler, M.D. OD
09-CH-0063 Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids Pamela Stratton, M.D. RE
09-CH-0085 Global Study of Women's Health Pamela Stratton, M.D. RE
09-CH-0180 Non-Invasive Non-Ionizing Polarized Imaging System to Assess Structure of Cervix Amir Gandjbakhche, Ph.D. IM
09-CH-0185 Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl Cysteine Forbes D. Porter, M.D. DE
09-CH-0203 Cholesterol in Autism Spectrum Disorder (ASD): Characterization and Treatment Forbes D. Porter, M.D. DE
09-CH-0213 Malaria Transmission-Blocking Pfs25-Pfs25 Conjugate Vaccine Rachel Schneerson, M.D. DM
09-CH-N014 The Effect of Vaginal Progesterone Administration in the Prevention of Preterm Birth in Women with a Short Cervix Roberto Romero, M.D. PR
09-CH-N023 Health Behaviors in School-Age Children: 2009/2010 Ronald Iannotti, Ph.D. PR
09-CH-N083 The National Children's Study - Pilot Protocol Steven Hirschfeld, M.D. PB
09-CH-N152 The National Standard for Normal Fetal Growth Jun Zhang, M.D. EB
09-CH-N165 Preventing Motor Vehicle Crashes Among Young Drivers: Evaluation of the Checkpoints Program Presented by the American Automobile Association Bruce Simons-Morton, M.D. PR
09-CH-N231 Health Behavior in School-Age Children: NEXT Longitudinal Study 2009-2013 Ronald Iannotti, Ph.D. PR
09-CH-N234 Cultivating Healthy Environments in Families with Type 1 Diabetes (CHEF) Tonja R. Nansel, Ph.D. PR
84-CH-0169 Endocrine Studies of Healthy Children Jack A. Yanovski, M.D. DE
88-CH-0032 Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood Status Marc H. Bornstein, Ph.D. CE
90-CH-0149 Early Copper Histidine Therapy in Menkes Disease Stephen G. Kaler, M.D. OD
91-CH-0127 Ovarian Follicle Function in Patients with Premature Ovarian Failure Lawrence M. Nelson, M.D. RE
92-CH-0011 Treatment of Hypoparathyroidism with Synthetic Human Parathyroid Hormone 1-34 Karen K. Winer, M.D. RE
92-CH-0034 Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IV Joan C. Marini, M.D. BE
92-CH-0223 Autoimmune Premature Ovarian Failure: A Controlled Trial of Alternate-Day Prednisone Therapy Lawrence M. Nelson, M.D. RE
95-CH-0059 Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related Conditions Constantine A. Stratakis, M.D. DE
95-CH-0104 Internal Jugular Vein Sampling for ACTH Levels for the Differential Diagnosis of Cushing Syndrome Lynnette K. Nieman, M.D. RE
95-CH-0110 Endometrial Mediators of Gonadal Steroid Action Lynnette K. Nieman, M.D. RE
96-CH-0033 An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal Hyperplasia Deborah P. Merke, M.D. OD
96-CH-0101 Population Differences in the Insulin Sensitivity, Resting Energy Expenditure, and Body Composition of Overweight Children and Children of Overweight Parents Jack A. Yanovski, M.D. DE
97-CH-0064 Evaluation and Intervention for Ambulation, Basilar Invagination, and Secondary Effects of Osteogenesis Imperfecta Joan C. Marini, M.D. BE
97-CH-0076 A Clinical and Genetic Investigation of Pituitary Tumors and Related Hypothalmic Disorders Constantine A. Stratakis, M.D. DE
98-CH-0081 Clinical and Basic Investigations into Smith-Lemli-Opitz Syndrome Forbes D. Porter, M.D. DE
98-CH-0111 Safety and Efficacy of Orlistat (Xenical, Hoffmann LaRoche) in African American and Caucasian Children and Adolescents with Obesity-Related Comorbid Conditions Jack A. Yanovski, M.D. DE
98-CH-0155 Categorization Based on Motion-Carried Information in Infancy Marc H. Bornstein, Ph.D. CE
99-CH-0055 New Imaging Modalities in the Evaluation of Patients with Ectopic Cushing Syndrome Lynnette K. Nieman, M.D. RE
99-CH-0103 Evaluation of Women with Endocrine and Reproductive-Related Conditions Alicia Y. Armstrong, M.D. RE
OH95-CH-N040 Use of a Perinatal Database and Biologic Tissue Bank at the Perinatology Research Branch (PRB) Roberto Romero, M.D. PR
OH97-CH-N065 Fetal Anatomy by Three-Dimensional Ultrasound Roberto Romero, M.D. PR
OH97-CH-N066 Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients with Preterm Labor and Premature Rupture of Membranes Roberto Romero, M.D. PR
OH97-CH-N067 Biological Markers of Disease in the Prediction of Preterm Delivery, Preeclampsia and Intra-Uterine Growth Retardation: A Longitudinal Study Roberto Romero, M.D. PR
OH97-CH-N068 Fetal Growth Evaluation by Three-Dimensional Ultrasound Roberto Romero, M.D. PR
OH98-CH-N001 Establishment of a Clinical Perinatal Database and Bank of Biological Materials Roberto Romero, M.D. PR
OH98-CH-N016 Cervical Volume by Three-Dimensional Ultrasound as a Predictor of Preterm Delivery Roberto Romero, M.D. PR
OH98-CH-N018 Early Pregnancy Evaluation by Three-Dimensional Ultrasound Roberto Romero, M.D. PR
OH99-CH-N023 Longitudinal Study of Vaginal Flora Mark Klebanoff, M.D. EB
OH99-CH-N050 Evaluation of the Safety, Immunogenicity and Compatibility with DTP of an Investigational Vi-rEPA(2) Conjugate Vaccine for Typhoid Fever When Administered to Infants in Vietnam Concurrently with DTP Shousun C. Szu, Ph.D. DM
OH99-CH-N056 Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition Roberto Romero, M.D. PR
Pilot Study of L-DOPS for Dysautonomia in Menkes Disease and Occipital Horn Syndrome Stephen G. Kaler, M.D. OD